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TURNING PRECISION APTAMERS INTO A NEW ERA OF MEDICINE

We are harnessing the power of aptamers to develop life-changing treatments for neurodegenerative diseases and cancer.

Deaths

609,820

Cost of care

>$240B

Deaths

272,644

With rising diagnoses and escalating costs for cancer, the demand for effective treatments is more pressing than ever.

4.7 to 6.0 million individuals in the U.S. suffer from CNS diseases

2023 cost of care

$800 bn

Most treatments today only offer limited symptom management. And millions of patients are left without a cure.

The power of precision aptamers

Opprtna is advancing the therapeutic potential of premium aptamers.

We take an underexplored angle to aptamer-based drug development. Using disease biology as our blueprint and Mother Nature as our inspiration, we target key proteins that bind to RNA/DNA.

1

Novel modality

Pioneering a novel drug modality that targets and stops disease-related proteins using DNA molecules.

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2

Targeted and safe

Approach ensures targeted and safe delivery, transforming the treatment landscape for patients previously deemed untreatable.

Patient with Healthcare Nurse

3

Potential applications

Science holds promise as evidenced by initial success with select targets in neurodegenerative and oncology indications.

Pipetting Samples

Leadership

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Ganesh Iyer, PhD

CEO & Founder

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Cindy Benod, PhD, MBA

COO/CBO

A powerhouse of scientific excellence, disease expertise, and operational grit. We have built transformative departments and organizations, turning visionary ideas into tangible realities.

Advisors

Paloma  Giangrande, PhD

CTO, Eleven Therapeutics
VP (Platform and Delivery), Wave Life Sciences
Editor in Chief, Mol Therap Nucleic Acids

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Piet Herdwjn, PhD

Professor, KU Leuven - Laboratory of Medicinal Chemistry, Belgium

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May Khanna, PhD

Co-Founder of Regulonix, LLC, Regenerix, LLC and Eternum Analytics, LLC
Assistant Dean and Associate Professor, Univ of Florida

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Rachit Bakshi, PhD

Assistant Professor, Harvard Medical School

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Mother and a Child

Opprtna is on a mission to treat the untreatable, using a novel modality that holds the potential for safer, more effective therapies. Our ambition is to empower patients, offering real hope and multiple avenues to overcome their health challenges.

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